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Steve Woods, Ph.D. Randy Seeley, Ph.D.
Price Schedule
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Energy Metabolism Core
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Obesity is the major predisposing risk factor for type II diabetes. This
core provides comprehensive set of measurements of food intake, energy expenditure
(including use of indirect calorimetry) and body fat composition. The core
is co-directed by Drs. Steve Woods
and Randy Seeley
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Test Descriptions, References and Data |
Test name:
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Food Intake and Body Weight Measurements (#C1040)
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Keywords:
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Dietary fat, diet-induced obesity, obesity
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Description:
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We will measure body wieght and food intake on low fat diets to determine
susceptibiliy to diet induced obesity. Mice will be placed on a high
fat (40% calories from fat) or low fat (8% calories from fat) diet. Body
weights and food intakes will be measured two times per week. |
References:
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foodintake.pdf
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Test name:
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Carcass Analysis (#C1041)
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Keywords:
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carcass analysis, total body fat, ether extraction, obesity, body composition
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Description:
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Total carcass analysis will reveal absolute amounts of body fat, lean
tissue and body water via freeze dehydration followed by either extraction. |
References:
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carcanal.pdf
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Test name:
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Energy Expenditure Measurements (#C1042)
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Keywords:
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oxygen consumption, CO2 production, respiratory quotient, basal metabolic
rate, obesity
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Description:
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Both total energy expenditure and relative rates of carbohydrate versus
fat oxidation will be determined via indirect calorimetry |
References:
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energyexp.pdf
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Test name:
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Hypothalamic Gene Expression (#C1043)
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Keywords:
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chypothalamus, in situ hybridization, obesity, neuropeptide Y, NPY,
melanocortins
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Description:
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We will assess the relative activation of a number of hypothalamic petidergic
systems implicated in the control of body weight. The primary measure
for the activation or inhibition of these systems will be measuring relative
mRNA expression using in situ hybridization. |
References:
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hypoexp.pdf
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